"Piralgin": composition, analogs, reviews and instructions for use
What is the drug "Piralgin"? The composition of this drug, its price, analogues and instructions for use will be described in detail below. We will also tell you about the cases in which this drug is prescribed, and in what situations its use is undesirable and can harm.
General information about tablets
Have you ever heard of a drug like Piralgin? Its composition is such that it contributes to the rapid analgesic effect. This medicine belongs to nonsteroidal anti-inflammatory drugs. It also acts as an opioid and psychostimulant drug.
The drug "Piralgin": composition and the form of
The composition of the mentioned medicinal product includes the following components:
- Active substances: sodium metamizol (i.e. analgin) - 300 mg, phenobarbital - 10 mg, naproxen - 100 mg, codeine - 8 mg and caffeine - 50 mg.
- Auxiliary components: potato starch, magnesium stearate and talc.
In the sale of the drug "Piralgin" comes in the form of flat-cylindrical tablets, which are chamfered and at risk, as well as white and yellow or cream color.
Pharmacological characteristics of the drug
What properties does the drug "Piralgin" (the composition of the drug was presented above)? It is a combination drug with properties that are characteristic of non-narcotic analgesics and NSAIDs.
Due to the content of naproxen and metamizole, this drug acts as an antipyretic, analgesic and anti-inflammatory drug. As for the substance phenobarbital, it gives a sedative effect.
Headaches, which are aggravated by migraines, can reduce caffeine, leading to dilation of the blood vessels of the heart, muscles, kidneys and brain.
In addition, tablets "Piralgin" can increase the pressure in hypotension, as well as increase the patient's performance, reduce drowsiness and fatigue.
Codeine, which is part of the drug, suppresses the excessive excitability of the cough center and hasanalgesic effect. This happens due to the excitation of peripheral tissues and opiate receptors of the central nervous system.
What happens if you take the drug "Piralgin"? Reviews of the drug states that its administration leads to the stimulation of the antinociceptive system (that is, anesthetic), which noticeably facilitates the condition of patients with a cold.
Such a drug inhibits respiratory function, but much less than morphine. Also, when a person takes a drug, he is less likely to have nausea, cases of miosis, vomiting, and constipation. This is due to the fact that the tablets relax the smooth muscles of the intestine, reduce peristalsis and spasms of sphincters. This happens due to the activation of opioid receptors.
How long does Piralgin medication work? Reviews of this tool often contain information that the duration of the drug effect is about 4-6 hours.
Pharmacokinetics of the drug
Where is the drug "Piralgin" absorbed? The instruction of this medication states that all substances (caffeine, metamizole sodium, codeine and phenobarbital) are absorbed only in the gastrointestinal tract, forming an active metabolite.At the same time, they are excreted through the kidneys along with urine and bile.
When should I take pills? Price and indications for taking the drug
This drug is recommended to take with moderately pronounced pain, having a different origin. As a rule, it is used during menstruation, migraine, headache and toothache, radiculitis, pain in muscle tissues, joints, neuralgia, as well as for catarrhal diseases and febrile syndrome.
How much do the pills cost? Their price varies from 90 to 110 Russian rubles for 10 pieces. You can purchase this drug at any pharmacy.
Contraindications to taking the drug
In what cases it is not recommended to take the drug "Piralgin", the price of which has a relatively low cost? This remedy has the following contraindications:
- acute renal as well as liver failure;
- G6PD deficiency;
- various blood disorders;
- bronchial asthma, as well as conditions that are accompanied by depression of the respiratory system;
- peptic ulcer disease of the digestive organs (especially in the acute stage);
- acute myocardial infarction;
- hypersensitivity to the drug;
- traumatic brain injury;
- breastfeeding period;
- arterial hypertension;
- alcohol intoxication;
- the presence of glaucoma;
- age up to 12 years.
It should be noted and the fact that the drug "Piralgin" should be taken with caution to the elderly and people with gastric ulcer and 12 duodenal ulcer.
After taking the mentioned drug, the patient can observe the following undesirable effects:
- allergic reactions on the skin and mucous membranes;
- decreased psychomotor reactions and drowsiness;
- vomiting, nausea, and constipation;
- leukopenia, agranulocytosis and granulocytopenia.
It should also be noted that the uncontrolled and long-term use of the drug in high doses can easily lead to addiction, which will manifest itself in a weakening of the analgesic effect. Also, the patient may have impaired liver and kidney function.
Symptoms of drug overdose
In case of overdose, the patient may show the following symptoms: vomiting, gastralgia, tachycardia, nausea, depressed respiration and arrhythmia.In such cases, it is necessary to stop vomiting, as well as urgently flush the stomach by taking activated charcoal. In addition, symptomatic therapy is required.
In order to avoid overdosing with the drug, before using it, you should read the instructions or contact your doctor.
Method of use of the drug
Now you know what the drug Piralgin is used for. Instructions for use of this tool will be presented below.
- Adults are prescribed 1 tablet three times a day after meals.
- Children older than 7 years recommended half of the adult dose.
The maximum number of tablets per day - 4 pieces. The duration of the drug should be 2 or 3 days (not more than one week).
The drug "Piralgin" should not be taken without prior consultation with your doctor for more than 3 days with febrile syndrome and more than 5 days with pain. Taking the drug in conjunction with caffeinated foods (tea or coffee) can easily trigger overdose symptoms.
If long-term drug treatment is required (more than 1 week), then monitoring of the state of the liver and peripheral blood is necessary.
When using this medication, you should be very careful when working with complex mechanisms, driving vehicles, as well as in classes that require a high concentration of attention, acute vision and responsiveness of psychomotor reactions.
It is impossible not to say that during treatment with Piralgin it is necessary to abandon the use of any alcoholic beverages.
Interaction with other drugs
Simultaneous use of the drug "Piralgin" with non-narcotic analgesics may cause an increase in toxic effects. Tricyclic antidepressants, contraceptives and allopurinol sometimes increase the toxicity of metamizole sodium (i.e. analgin). Its action can reduce phenylbutazone and barbiturates.
The analgesic effect of the medication “Piralgin” is enhanced by sedatives and tranquilizers. Simultaneous use of cyclosporine and metamizole sodium leads to a decrease in the level of the first in the blood.
Analogues of the drug
What to do if the patient could not find the drug "Piralgin"? Analogs of this drug are sold in almost any pharmacy.They have similar pharmacological characteristics and have a similar chemical composition. Although some excipients may still vary.
So, among the analogues of the drug "Piralgin", the following drugs can be highlighted: "Spazmoanalgan", "Pentalgin with drotaverin", "Trigan-D", "Nurofen plus", "Spazmalin", "Nebalgan", "Bellalgin", "Paracetamol Extra "," Bralangin "," Next "," Revalgin "," Brustan "," Unispaz "," Spazmalgon "," Sedalgin Neo "," Pentalgin plus "," Dolospa "," Benalgin "," Neurodiclovit ", Plenalgin "," Santotralgin "," Caffetin "," Pentalgin ICN "," Brahl "," Aspirin with Vitamin C "," Spasmoblok "," Alka-Seltzer "," Zaldiar "," Aspivit "," Dolarin "," Bioralgin "," Daleron S "," Spazgan "," Parkocet "," Plivalgin "," Ring N ", Sedal M", "Tsefekon M", "Tsitrapak", "Santoperalgin", "Renalgan", "Spazdolzin", " Tempalgin ”,“ Spazmalgin ”,“ Spazmogard ”,“ Tsefekon N ”,“ Maksigan ”,“ Anapirin ”,“ Tempaldol ”,“ Tempanginol ”,“ Andipal ”,“ Femizol ”,“ Flyuzioz ”,“ Sedalgin Plus ”,“ Baralgetas "," Tsefekon P "and so on.
The shelf life of the drug and its storage conditions
It is recommended to store the drug "Piralgin" in a place protected from sunlight. Also, it is undesirable to leave it where small children can find it. The shelf life of this medication is exactly two years from the date of production.